Human NGAL, 50 ug

Human NGAL, 50 ug

24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; HNL; LCN2; lipocalin 2 (oncogene 24p3); lipocalin 2; Lipocalin2; Lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; NGALlipocalin-2; Oncogene 24p3; p25; Siderocalin; Uterocalin

$350.00

NGAL (Neutrophil Gelatinase-Associated Lipocalin) is a member of Lipocalin family sharing a highly conserved fold with an eight-stranded antiparallel beta barrel, and it acts as a transporters, carrying small molecules to specific cells, and existing in monomeric and homo- and heterodimeric forms, the latter as a dimer with human neutrophil gelatinases (MMP-9). It is expressed in most tissues normally exposed to microorganism, and its synthesis is induced in epithelial cells during inflammation. NGAL has been implicated in a variety of processes including cell differentiation, tumorigenesis, and apoptosis, and can alter the invasive and metastatic behavior of Ras-transformed breast cancer cells by reversing epithelial to mesenchymal transition inducing activity of Ras. (1-5)

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