Human IL28B, 50 ug

Human IL28B, 50 ug

interleukin-28B; IFN-lambda 3; IL28B; IL-28B; IL28C; interferon, lambda 3

$980.00

IL-28B (also named interferon-lambda 3, IFN-lambda 3), IL-28A (IFN-lambda 2) and IL-29 (IFN-lambda 1) are type III interferons as class II cytokine receptor ligands. They signal through a widely expressed receptor that is a heterodimer of the IL-10 receptor beta and IL-28 receptor alpha, activating similar pathways, including JAK/STAT signaling pathway. Both type I and III IFNs induce anti viral activity and up regulate MHC class I antigen expression. In vivo Type III IFNs have shown anti-viral activity, anti-proliferative and antitumor activity (1-5).

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